Best Enzymatic Cleaner: Top Choices for 2024 You Can’t Miss!

When it comes to cleaning products, enzymatic cleaners are among the best options available. Their ability to break down tough stains, odors, and organic matter makes them highly effective for various cleaning tasks around the house, especially for pet owners. In 2024, if you’re looking for the best enzymatic cleaner, you’ll want to check out the top 10 enzymatic cleaners available on Amazon. Here, we will review these products, highlighting their unique features and benefits, while also providing a comprehensive buying guide to help you make an informed choice.

# Preview Product Rating Price
1 AmazonCommercial Multi-Purpose Enzyme Cleaner, Mint, 1 gallon, 128 fl oz (Pack of 1) AmazonCommercial Multi-Purpose Enzyme Cleaner, Mint, 1 gallon, 128 fl oz (Pack of 1) No ratings yet $33.29
2 Rocco & Roxie Supply Co. Stain & Odor Eliminator for Strong Odor, 32oz Enzyme Pet Odor Eliminator for Home, Carpet Stain Remover for Cats & Dog Pee, Enzymatic Cat Urine Destroyer, Carpet Cleaner Spray Rocco & Roxie Supply Co. Stain & Odor Eliminator for Strong Odor, 32oz Enzyme Pet Odor Eliminator... No ratings yet $19.31
3 Simple Solution Extreme Pet Stain and Odor Eliminator Spray, Enzymatic Cleaner With 3X Pro-Bacteria Cleaning Power for Dogs & Cats, Strong Urine, Pee and Poop Smell Remover for Carpets & Floors, 32 oz Simple Solution Extreme Pet Stain and Odor Eliminator Spray, Enzymatic Cleaner With 3X Pro-Bacteria... No ratings yet $8.90
4 McKesson Multi-Enzymatic Cleanser, for Surgical Instruments, Eucalyptus Spearmint Scent, 1 gal, 1 Count, 1 Pack McKesson Multi-Enzymatic Cleanser, for Surgical Instruments, Eucalyptus Spearmint Scent, 1 gal, 1... No ratings yet $33.01
5 Nature's Miracle Dog Stain and Odor Remover, Everyday Mess Enzymatic Formula, 32 fl oz Nature's Miracle Dog Stain and Odor Remover, Everyday Mess Enzymatic Formula, 32 fl oz No ratings yet $10.75
6 Zeiff Pro-Grade Multi-Purpose Probiotic Enzyme Cleaner - Powerful Cleaning & Odor Eliminating Formula For Professional & Home Surfaces - 32 Ounce - Fragrance Free Zeiff Pro-Grade Multi-Purpose Probiotic Enzyme Cleaner - Powerful Cleaning & Odor Eliminating... No ratings yet $9.97
7 Enzyme Laundry Booster Odor Remover - 2 lbs Unscented Enzymatic Clothes Stain Cleaner Powder, Natural Deodorizer with Bio Active Enzymes, Detergent Additive Eliminator for Sweat, Oil, Blood - 64 Loads Enzyme Laundry Booster Odor Remover - 2 lbs Unscented Enzymatic Clothes Stain Cleaner Powder,... No ratings yet $19.99
8 Biokleen Bac-Out Enzyme Stain & Odor Remover - 128 Ounces - Destroys Stains & Odors Safely, for Pet Stains, Laundry, Diapers, Wine, Carpets, & More, Eco-Friendly, Non-Toxic Biokleen Bac-Out Enzyme Stain & Odor Remover - 128 Ounces - Destroys Stains & Odors Safely, for Pet... No ratings yet $34.98
9 CSI Central Solutions Multi Enzymatic Cleaner - Hospital Grade Medical Instrument Cleaner for Presoak, For Ultrasonic Cleaner Machines and Manual Processing, 1 Gal CSI Central Solutions Multi Enzymatic Cleaner - Hospital Grade Medical Instrument Cleaner for... $33.98
10 Nature's Miracle Advanced Dog Stain and Odor Eliminator Spray, Severe Mess Enzymatic Formula, 32 fl oz Nature's Miracle Advanced Dog Stain and Odor Eliminator Spray, Severe Mess Enzymatic Formula, 32 fl... No ratings yet $13.55

Top 10 Best Enzymatic Cleaners on Amazon

1. Nature’s Miracle Stain & Odor Remover

Nature’s Miracle has established itself as a go-to brand for pet owners seeking effective cleaning solutions. This enzymatic cleaner targets tough stains and odors caused by pets, using natural enzymes to break down organic waste. It’s ideal for carpets, hard floors, and furniture upholstery. Many users rave about its ability to eliminate even the strongest pet-related odors, making it a top contender for the best enzymatic cleaner.

This product is also non-toxic and safe to use around pets and children, ensuring peace of mind while cleaning.

Bestseller No. 1
Nature’s Miracle Stain And Odor Remover Dog 24 Ounces, Odor Control Formula, Spray
Nature’s Miracle Stain And Odor Remover Dog 24 Ounces, Odor Control Formula, Spray
  • SPOT STAIN & ODOR REMOVER: Begins to break down and remove stains immediately on contact.
  • LIGHT CITRUS SCENT: Dog odor control formula gets your home smelling clean again.
  • ENZYMATIC FORMULA: Continues working as long as any bio-based mess is still present.
  • SAFE FOR PETS AND HOME: When used and stored as directed, this formula can be used around your pets.
  • TRUSTED BRAND: From the maker of Nature’s Miracle products, the pet stain and odor removing brand you trust… because it works.

2. Rocco & Roxie Professional Strength Stain Remover

Rocco & Roxie’s Professional Strength Stain Remover is another top choice for pet owners. This cleaner features a powerful formula that penetrates deep into carpets and upholstery to break down stains and odors. Its enzymatic action guarantees that even the most stubborn messes are dealt with effectively. The product is also free from harsh chemicals, making it safe for daily use in homes with pets and children.

This cleaner gets high marks for its effectiveness on both old and new stains, offering versatility that many pet owners appreciate.

Bestseller No. 1
Rocco & Roxie Oxy Stain Remover - Oxygen Powered Carpet Cleaner Spray - Spot Cleaner for Upholstery, Couch, Laundry, Rug, Clothes, Car Seat, Mattress, Sofa, and More. - Pet & Baby Stains
Rocco & Roxie Oxy Stain Remover - Oxygen Powered Carpet Cleaner Spray - Spot Cleaner for Upholstery, Couch, Laundry, Rug, Clothes, Car Seat, Mattress, Sofa, and More. - Pet & Baby Stains
  • Fast Acting: Activated Oxygen technology breaks up stains right before your eyes; Eliminates stains at the source so they never come back
  • Tough: Our Professional Strength Oxy formula will remove your toughest set-in stains caused by urine, feces, vomit, blood, dirt, grass, juice, chocolate, coffee, tea, blueberries, tomato sauce, ink, red wine and much more
  • Gentle: Chlorine free and color safe; Certified Safe for use on all carpet types; We have earned the Seal of Approval from the trusted Carpet and Rug Institute (CRI);Will not leave residue that will attract dirt or leave your carpet feeling crunchy
  • Multi-Purpose: Use it to get out tough stains on carpet, upholstery, laundry, and all water-safe surfaces
  • Safe: Safe to use around pets and children; Non-aerosol - No hazardous propellants

3. Biokleen Bac-Out Stain Remover

Another fantastic enzymatic cleaner is Biokleen Bac-Out Stain Remover. This product contains live enzyme cultures and is designed to break down organic stains and odors effortlessly. It can be used on a variety of surfaces, including carpets, upholstery, fabric, and even laundry. Customers often highlight its effectiveness on both pet stains and general spills, positioning it as a versatile addition to any cleaning arsenal.

Moreover, Biokleen prides itself on being eco-friendly and free of artificial fragrances and color additives, which is a major plus for environmentally conscious consumers.

Bestseller No. 1
Biokleen Bac-Out Carpet Stain Remover Enzymatic, Destroys Stains & Odors Safely, for Pet Urine, Laundry, Diapers, Wine, Carpets, More, Eco-Friendly, Plant-Based
Biokleen Bac-Out Carpet Stain Remover Enzymatic, Destroys Stains & Odors Safely, for Pet Urine, Laundry, Diapers, Wine, Carpets, More, Eco-Friendly, Plant-Based
  • CARPET STAIN AND ODOR REMOVER: Bac-Out safely works wonders on pet accidents, wine spills on carpets and couches, cloth diapers and pails, laundry, disposals, garbage cans and much more.
  • FULL STRENGTH: Bac-Out's formula is ready to use. No diluting necessary.
  • BIO-ACTIVE FORMULA: A unique blend of live enzyme cultures breakdown and absorb organic material. It's a more natural way to remove buildup and stinky odors.
  • PLANT-BASED CLEANER: Bac-Out uses a plant-based, eco-friendly solution with no artificial fragrances or dyes. Our products never contain phosphates, chlorine, ammonia, or brighteners.
  • MADE IN THE USA: We use biodegradable ingredients, never test on animals, and are manufactured in the USA with US and imported parts

4. Simple Green Pro 5 Cleaner

Simple Green Pro 5 Cleaner is a professional-grade enzymatic cleaner that can tackle tough grease, oil, and stains with ease. It’s not only beneficial for pet owners but also ideal for industrial use. This cleaner employs a powerful but safe enzymatic solution capable of breaking down stubborn substances on multiple surface types.

Users appreciate its versatility, as it works well on not just textiles but also hard surfaces, making it a favorite for industrial cleaning professionals.

OFF -$1.93Bestseller No. 1
Simple Green 30501 d Pro 5 Disinfectant, 1 gal Bottle
Simple Green 30501 d Pro 5 Disinfectant, 1 gal Bottle
  • Simple Green d Pro 5 is a one-step disinfectant that has a high level of active ingredients for heightened efficacy and economy
  • It can be used in food production, processing, and service facilities
  • Simple Green d Pro 5 has an extensive efficacy list including Hepatitis B and C, Canine Distemper Virus, and Avian Influenza
  • Simple Green d Pro 5 is meant to be absolutely effective on the bacterial, viral, and fungal threats that invade our lives
  • Ideal for athletic facilities, bars/restaurants, barber shops, bathrooms, beauty salons, business and office buildings, cafeterias, convenience stores, correctional facilities and day care centers

5. PetSafe Remove Odor and Stain Eliminator

For those who are looking for a product dedicated to combatting pet-related messes, the PetSafe Remove Odor and Stain Eliminator is worth considering. This enzymatic cleaner is specially formulated to eliminate odors and stains from pet urine, feces, blood, and vomit. It penetrates deep into surfaces to eliminate the source of the odor rather than just masking it.

Many users praise its efficiency in eliminating lingering odors and preventing pets from re-soiling the same area.

Bestseller No. 1
Rocco & Roxie Supply Co. Stain & Odor Eliminator for Strong Odor, 32oz Enzyme Pet Odor Eliminator for Home, Carpet Stain Remover for Cats & Dog Pee, Enzymatic Cat Urine Destroyer, Carpet Cleaner Spray
Rocco & Roxie Supply Co. Stain & Odor Eliminator for Strong Odor, 32oz Enzyme Pet Odor Eliminator for Home, Carpet Stain Remover for Cats & Dog Pee, Enzymatic Cat Urine Destroyer, Carpet Cleaner Spray
  • Certified Gentle And Safe: Chlorine free and color safe; Safe to use around pets and children; No hazardous propellants, no residue left behind. So gentle it’s been Certified Safe for all carpets, earning the Seal of Approval by the trusted Carpet and Rug Institute (cri)
  • Eliminates Stains, Odors and Residue: If it’s gross, it’s gone; Not just the stain, but the stink; From stinky yellow pet urine and feces to vomit and other organic spills, our professional strength formula tackles them all
  • Every Surface, Every Time: For use on carpets, floors, furniture, clothing, litter boxes, kennels, carriers, all pet living and sleeping areas—anywhere stains happen
  • Enzyme Activated: The key is getting to the problem deep-down; This spray contains natural enzymes that are activated on contact with odors and stains, feeding on ammonia crystals and organic matter until they are completely eliminated
  • Buy With Confidence: You want the best for your best friend; We do, too; If you are not satisfied with the performance of this product, contact us; We are determined to make it right

6. OxiClean MaxForce Spray

OxiClean MaxForce Spray utilizes the power of OxiClean to tackle tough stains, but it also contains enzymes that help break down organic material. This makes it effective not just for food stains, but also for pet messes. Users love its ability to lift set-in stains and odors, making it a practical solution for both pre-treating laundry and cleaning carpets.

Its convenience in a spray bottle allows for easy application, making it an accessible option for quick clean-ups.

OFF -$4.02Bestseller No. 1
OxiClean Max Force Laundry Stain Remover Spray Refill, 48 fl oz
OxiClean Max Force Laundry Stain Remover Spray Refill, 48 fl oz
  • One 48 fl oz bottle of OxiClean Max Force Laundry Stain Remover Spray Refill tackles your stubborn and dried-in laundry stains​
  • OxiClean Max Force stain spray lets you pretreat stains now, then wash up to seven days later for cleaning that fits your schedule​
  • Powerful laundry spot remover for oil, grease, make-up, blood, grass, soil, clay, ink, food, drinks, and kid and baby stains​
  • Laundry stain remover for clothes is 100 percent dye free and chlorine free, and safe for use on all machine-washable whites and colored fabrics, even kid and baby clothes​
  • Spray directly on stains until saturated, let stand five minutes or up to seven days before washing with detergent in the warmest water garment will accept. For whiter, brighter clothes, add OxiClean Versatile Stain Remover to washer per label directions

7. Zorb-It-Up Odor Eliminator

Zorb-It-Up is a unique enzymatic cleaner designed to absorb and neutralize odors rather than just masking them. This product works exceptionally well in challenging situations, such as basement cleanup or other areas within the house where moisture or organic waste can create odors. Many users have reported that it can effectively eliminate musty smells as well.

The absorbent nature of this cleaner allows it to be a multi-faceted tool in your cleaning kit.

OFF -$6.01Bestseller No. 1
ZORBX Unscented Odor Eliminator for Strong Odor - Used in Hospitals & Healthcare Facilities | Advanced Trusted Formula, Fast-Acting Odor Remover Spray for Dog, Cat, House & Carpet (64 oz)
ZORBX Unscented Odor Eliminator for Strong Odor - Used in Hospitals & Healthcare Facilities | Advanced Trusted Formula, Fast-Acting Odor Remover Spray for Dog, Cat, House & Carpet (64 oz)
  • INSTANT, PERMANENT, ADVANCED PATENTED MULTIPURPOSE ODOR REMOVAL FORMULA: We continue utilizing safer, superior, and more advanced odor removal technologies to provide our customers with the best products. With just a little splash of ZORBX odor remover, you will be able to tackle all kinds of odors like professionals no matter how strong they are. Our odor remover formula is the permanent solution to your odor problems.
  • EXTRA STRENGTH, SAFER, ECO-FRIENDLY ODOR ABSORBERS FOR ROOMS: Non-toxic ingredients in ZORBX multipurpose odor remover are derived from natural resources. This odor remover is safer for people, pets, and the planet. Our unscented odor neutralizer will help remove foul and funky odors without harming you, your pet, or the planet. Our ZORBX odor eaters will make your surroundings and furry friends smell clean and fresh!
  • 64 OZ SPRAY: Our odor remover comes in a convenient 64 oz. spray bottle, perfect for freshening up the air anywhere you go. Keep odor remover spray bottle in your car or travel bag to quickly eliminate unpleasant smells while on the go. Carpet odor remover is ideal for outdoor travel and everyday use at home, in garages, basements, and bathrooms.
  • WHY BUY OUR PRODUCT? You must be wondering why choose our product when it's available in different sizes. Our product offers fast-acting smoke, urine, hospital odor remover solutions to help you breathe fresh air wherever you go. With this spray, you will never run out of odor exterminator solutions—the perfect spray for fighting all kinds of odors.
  • TRUSTED BRAND: The main goal of our company ZORBX is to provide our customers with high-quality products. Also, all of our odor remover solutions are strictly inspected before we ship them out to you. If you are not happy with our strong odor remover for any reason, please contact us. We will take care of it in no time! Your satisfaction is our priority.

8. Bissell Pet Pro Oxy Stain Destroyer

Bissell’s Pet Pro Oxy Stain Destroyer is an enzymatic carpet cleaner formulated specifically for breaking down pet stains. With its unique dual-action formula, it not only cleans stains but also permanently neutralizes odors, making it a sought-after option for pet owners. Many users report that it outperforms competitors in treating embedded stains.

This product can be used with carpet cleaning machines or as a standalone spray, providing a flexible cleaning solution.

Bestseller No. 1
BISSELL PET PRO OXY Stain Destroyer for Carpet and Upholstery, 22 oz, 2 Pack, 17739, 22 Fl Oz (Pack of 2), 44
BISSELL PET PRO OXY Stain Destroyer for Carpet and Upholstery, 22 oz, 2 Pack, 17739, 22 Fl Oz (Pack of 2), 44
  • Every BISSELL purchase helps save pets. BISSELL proudly supports BISSELL Pet Foundation and its mission to help save homeless pets.
  • Permanent stain removal in 30 seconds
  • Instantly and permanently removes tough stains like tracked-in dirt, grass, mud, blood, pet stains and more
  • Eliminates tough pet odors and discourages pets from resoiling
  • Safe for kids and pets when used as directed

9. ToughGrade Professional Pet Stain & Odor Remover

ToughGrade’s Professional Pet Stain & Odor Remover boasts an advanced formula that penetrates deep to dissolve and eliminate stains and odors. It’s popular among users for its effectiveness and fast-acting nature, making it ideal for emergency clean-ups. With a non-toxic formula, it’s also safe for use around kids and pets.

Many users appreciate its capacity to handle various surfaces, making it a versatile choice.

Bestseller No. 1
Rocco & Roxie Supply Co. Stain & Odor Eliminator for Strong Odor, 32oz Enzyme Pet Odor Eliminator for Home, Carpet Stain Remover for Cats & Dog Pee, Enzymatic Cat Urine Destroyer, Carpet Cleaner Spray
Rocco & Roxie Supply Co. Stain & Odor Eliminator for Strong Odor, 32oz Enzyme Pet Odor Eliminator for Home, Carpet Stain Remover for Cats & Dog Pee, Enzymatic Cat Urine Destroyer, Carpet Cleaner Spray
  • Certified Gentle And Safe: Chlorine free and color safe; Safe to use around pets and children; No hazardous propellants, no residue left behind. So gentle it’s been Certified Safe for all carpets, earning the Seal of Approval by the trusted Carpet and Rug Institute (cri)
  • Eliminates Stains, Odors and Residue: If it’s gross, it’s gone; Not just the stain, but the stink; From stinky yellow pet urine and feces to vomit and other organic spills, our professional strength formula tackles them all
  • Every Surface, Every Time: For use on carpets, floors, furniture, clothing, litter boxes, kennels, carriers, all pet living and sleeping areas—anywhere stains happen
  • Enzyme Activated: The key is getting to the problem deep-down; This spray contains natural enzymes that are activated on contact with odors and stains, feeding on ammonia crystals and organic matter until they are completely eliminated
  • Buy With Confidence: You want the best for your best friend; We do, too; If you are not satisfied with the performance of this product, contact us; We are determined to make it right

10. Green Works Natural All-Purpose Cleaner

While not solely an enzymatic cleaner, Green Works Natural All-Purpose Cleaner contains biodegradable cleaning agents and enzymes. It’s great for general cleaning tasks around the house while still being tough on stains. Consumers love its pleasant scent and effectiveness on various surfaces, from kitchen counters to bathroom tiles.

This cleaner is best for those who want an eco-friendly option without sacrificing cleaning power.

Bestseller No. 1
Simple Green All Purpose Cleaner Concentrate 64 Fl Oz
Simple Green All Purpose Cleaner Concentrate 64 Fl Oz
  • All-purpose concentrated cleaner removes dirt, grease, and stains
  • Recognized by the U.S. EPA's Safer Choice Program
  • Cleans counters, carpet, floors, fabric, equipment and vehicles
  • Use full strength on heavy messes or dilute for daily cleaning
  • Cleans and leaves behind a refreshing sassafras scent

Buying Guide for Enzymatic Cleaners

When searching for the best enzymatic cleaner, it’s essential to consider several factors to ensure you choose a product that meets your specific needs. Here are some key aspects to look at:

1. Purpose

Identify what you primarily need the enzymatic cleaner for—pet stains, food spills, mold, or general cleaning. Different products excel in various areas, so choose one aligned with your requirements.

2. Surface Compatibility

Check whether the cleaner is suitable for the surfaces you plan to clean. Some products work well on carpets and upholstery, while others may be more effective on hard surfaces.

3. Ingredients

Opt for enzymatic cleaners that utilize natural, non-toxic ingredients if you have children or pets at home. This will ensure a safer cleaning experience.

4. Scent

Many enzymatic cleaners are fragrance-free or use essential oils for scent. Choose one that fits your preferences, especially if strong fragrances may be overpowering.

5. User Reviews

Before making a purchase, read user reviews to gauge product effectiveness based on real-world experiences. Look for feedback regarding odor control, stain elimination, and overall satisfaction.

6. Price

Finally, consider your budget. While some products may cost a bit more, the effectiveness could save you money on repeated purchases or professional cleaning services.

In conclusion, finding the best enzymatic cleaner can significantly simplify your cleaning routine. With the right choice, you can ensure your home stays fresh, clean, and free from pesky stains and odors. Whether you’re a pet owner or simply looking for an effective cleaner, the products reviewed above cater to a wide variety of needs.

Last update on 2024-09-20 / Affiliate links / Images from Amazon Product Advertising API | votechriscarrillo.com is a participant in the Amazon Associate program and will earn from qualifying purchases.

Leave a Reply

Your email address will not be published. Required fields are marked *